Michael Lewis

Lorna Casselton Memorial Scholarship

Joining us from: Wales, UK

Interdisciplinary Bioscience DTP (DPhil) (2023)

I am a doctoral researcher in the Department of Engineering Science, where my work focuses on artificial photosynthesis in bacteria, specifically Cupriavidus necator. Unlike plant photosynthesis, our system relies on a membrane-bound proton pump, rhodopsin, which generates a proton motive force upon illumination. This drives ATP synthesis and enhances cellular growth using CO₂ as the sole carbon source. Recently, we developed a machine-learning pipeline to spectrally tune the maximal absorbance wavelength of rhodopsin, leading to significantly improved growth performance. Using these engineered strains, I am now investigating novel metabolic strategies for the sustainable production of biofuels. Broadly, my research aims to contribute to low-carbon technologies that address climate change by converting renewable energy and CO₂ into useful fuels. 

As a relatively small graduate college, St Cross offers a friendly and close-knit community, making it easy to form meaningful connections with students from around the world. I particularly value the shared facilities between students and Fellows, which means we can have fascinating conversations during college dinners, halls, and formal events. My college tutor and the wider staff have been consistently supportive and approachable, always willing to help resolve any issues. 

I am very grateful to be a recipient of the Lorna Casselton Memorial Scholarship and for the support it has provided throughout my studies. I have also greatly enjoyed attending the annual Lorna Casselton Lecture.